Disclosed is a method for the treatment and resource utilization of acidic organic wastewater, comprising: (1) performing activated sludge treatment on acidic organic wastewater; and (2) performing microalgae treatment on the acidic organic wastewater treated in step (1). By means of the combination of activated sludge treatment and microalgae treatment, the present invention can significantly reduce the COD of the acidic organic wastewater. In some embodiments, the use of acclimated activated sludge or activated sludge having a specific microbial flora structure can not only improve the treatment efficiency while shortening the treatment time, but also omit a pH value adjustment step without causing sludge accumulation.