Invention Grant
- Patent Title: Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs
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Application No.: US16124901Application Date: 2018-09-07
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Publication No.: US12060574B2Publication Date: 2024-08-13
- Inventor: Eduardo N. Mitrani
- Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Applicant Address: IL Jerusalem
- Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Current Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Current Assignee Address: IL Jerusalem
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: IL 6820 2009.02.01
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61L27/36 ; A61L27/38 ; C12N5/071 ; C12N5/0735 ; A61K35/12

Abstract:
A composition of matter is provided comprising a devitalized, acellular tissue-derived scaffold seeded with differentiated cells, particularly pancreatic islet cells, wherein the cells can maintain cell-specific function or structure in culture on the scaffold. Methods of generating same and uses thereof are also provided.
Public/Granted literature
- US20180371407A1 METHODS OF GENERATING TISSUE USING DEVITALIZED, ACELLULAR SCAFFOLD MATRICES DERIVED FROM MICRO-ORGANS Public/Granted day:2018-12-27
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