A method for facilitating on-time delivery of temperature and time sensitive (TTS) shipments. The method includes receiving, by a processor of a computing device, entry of TTS shipping data. The method includes receiving an entry providing an identification of a location tracker that is collocated with the TTS package, the location tracker enabling the TTS package to be geographically tracked during shipping. Method includes receiving a total time limit for package delivery from a current time, and assigning at least one threshold time that precedes the total time limit; receiving, via a network connection to the location tracker, an update of a real-time location of the TTS package relative to an intended destination; in response to the total elapsed time surpassing one threshold, generating and forwarding a notification to an output device that includes a pre-configured notification message related to the time and/or temperature sensitivity of the TTS package.