A system is configurable to, over a frame capture time period, selectively activate an illuminator to alternately emit light from the illuminator and refrain from emitting light from the illuminator. The system is configurable to, over the frame capture time period, perform a plurality of sequential shutter operations to configure each image sensor pixel of an image sensor array to enable photon detection. The plurality of sequential shutter operations generates, for each image sensor pixel of the image sensor array, a plurality of binary counts indicating whether a photon was detected during each of the plurality of sequential shutter operations. The system is configurable to, based on a first set of binary counts of the plurality of binary counts, generate an ambient light image. The system is configurable to, based on a second set of binary counts of the plurality of binary counts, generate an illuminated image.