An accessory cuff is configured to reinforce a gown-glove interface to protect a wearer from exposure to potential pathogens or contaminants through vulnerabilities in the gown-glove interface. The accessory cuff includes a body extending from a proximal end to a distal end along a longitudinal axis. The body has a lumen extending therethrough from the proximal end to the distal end, and a wall surrounding the lumen. The accessory cuff is configured to create a fluid impervious barrier to prevent fluid from entering the lumen when the accessory cuff is sealed at the proximal end and the distal end.