A device for the continuous and real-time monitoring of bilirubin, comprises a housing that encloses a waterproof/splash proof body. The body comprises a bilirubin and temperature measuring module; a wearable biocompatible strap; a buckle; a display unit; a safety module; a learning module; a battery and charging unit; a switch; and a wireless connectivity facilitator. The bilirubin and temperature measuring module comprises: one or more light emitting sources; a microprocessor; one or more photodetectors; a filter; and an analogue to digital converter. The device can be configured to be mounted on a patient's wrist or any other body part like palm, earlobe, cheek, finger, forehead, and feet.