An information handling system presents audible sounds from audio information at an in-ear monitor having a speaker in a speaker housing that directs sound through a speaker tube. An angular alignment mechanism adjusts the angular orientation of the speaker tube relative to the speaker housing and a vertical alignment mechanism adjust the distance that the speaker tube extends out from the speaker housing. Position sensors detect the position of the ear tube so that an audio processor can apply the position to adjust the sound output from the speaker and the noise cancellation provided in response to external noise detected by a microphone within the speaker housing.