One or more devices, systems, methods and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for detecting external elastic lamina (EEL) and/or lumen edge(s) are provided herein. One or more embodiments provide at least one method, device, apparatus, system, or storage medium to comprehend information, including, but not limited to, molecular structure of a vessel, and to provide an ability to manipulate the vessel information. In addition to controlling one or more imaging modalities, the EEL detection techniques may operate for one or more applications, including, but not limited to, manual or automatic EEL detection, stent positioning, stent selection, co-registration, and imaging.