- Patent Title: Methods for treating lysosomal acid lipase deficiency in patients
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Application No.: US17854325Application Date: 2022-06-30
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Publication No.: US12076376B2Publication Date: 2024-09-03
- Inventor: Anthony Quinn
- Applicant: Alexion Pharmaceuticals, Inc.
- Applicant Address: US MA Boston
- Assignee: Alexion Pharmaceuticals, Inc.
- Current Assignee: Alexion Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- Main IPC: A61K38/46
- IPC: A61K38/46 ; A61K31/135 ; A61K31/138 ; A61K31/366 ; A61K31/397 ; A61K45/06 ; A61P3/06 ; C12N9/18 ; C12N9/20

Abstract:
The present invention provides methods of treating LAL deficiency comprising administering to a mammal a therapeutically effective amount of lysosomal acid lipase with an effective dosage frequency. Methods of improving growth and liver function, increasing LAL tissue concentration, and increasing LAL activity in a human patient suffering from LAL deficiency are also provided.
Public/Granted literature
- US20220362350A1 METHODS FOR TREATING LYSOSOMAL ACID LIPASE DEFICIENCY IN PATIENTS Public/Granted day:2022-11-17
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