Invention Grant
- Patent Title: Systems and methods for opening of a tissue barrier in primates
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Application No.: US17690523Application Date: 2022-03-09
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Publication No.: US12076590B2Publication Date: 2024-09-03
- Inventor: Elisa E. Konofagou , Fabrice Marquet , Yao-Sheng Tung
- Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Baker Botts L.L.P.
- Main IPC: A61N7/00
- IPC: A61N7/00 ; A61B8/08 ; A61B17/00 ; A61B17/22 ; A61B17/225 ; A61B90/00 ; A61B90/10
Abstract:
Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions.
Public/Granted literature
- US20220193457A1 SYSTEMS AND METHODS FOR OPENING OF A TISSUE BARRIER IN PRIMATES Public/Granted day:2022-06-23
Information query
