Invention Grant
- Patent Title: Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
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Application No.: US17442474Application Date: 2020-03-25
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Publication No.: US12077512B2Publication Date: 2024-09-03
- Inventor: David D. Ginty , Lauren L. Orefice , Jinbo Lee
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2020/024564 2020.03.25
- International Announcement: WO2020/198275A 2020.10.01
- Date entered country: 2021-09-23
- Main IPC: C07D243/24
- IPC: C07D243/24
Abstract:
The present invention provides novel peripherally-restricted benzodiazepines with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or Fragile X syndrome.
Public/Granted literature
- US20220162173A1 COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT Public/Granted day:2022-05-26
Information query
