Invention Grant
- Patent Title: Bicyclic pyridine derivative
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Application No.: US18506804Application Date: 2023-11-10
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Publication No.: US12077546B2Publication Date: 2024-09-03
- Inventor: Satoshi Adachi , Hidefumi Yoshinaga , Hajime Shibata , Yusuke Shioda , Riko Nagahama
- Applicant: Sumitomo Pharma Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: Sumitomo Pharma Co., Ltd.
- Current Assignee: Sumitomo Pharma Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP 21066825 2021.04.10 JP 21150394 2021.09.15
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P25/00 ; C07D213/65 ; C07D215/12 ; C07D221/04 ; C07D401/06 ; C07D491/048 ; C07D495/04

Abstract:
The present disclosure provides bicyclic pyridine derivatives.
A compound represented by formula I:
or a pharmaceutically acceptable salt thereof,
wherein
X is a oxygen atom, sulfur atom, NR, or CR′R″, n is 0 or 1, R1, R2a, R2b, R2c, R2d, R, R′ and R″ are each independently a hydrogen atom, a halogen atom, optionally substituted C1-6 alkyl, or an optionally substituted C6-10 aryl, or two of R2a, R2b, R2c, R2d, R, R′, and R″, together with a carbon atom or a nitrogen atom to which they are attached, form a 3- to 6-membered saturated carbocyclic ring or saturated heterocyclic ring, and R3a, R3b, R3c and R5a and R5b, are as defined in the description.
A compound represented by formula I:
or a pharmaceutically acceptable salt thereof,
wherein
X is a oxygen atom, sulfur atom, NR, or CR′R″, n is 0 or 1, R1, R2a, R2b, R2c, R2d, R, R′ and R″ are each independently a hydrogen atom, a halogen atom, optionally substituted C1-6 alkyl, or an optionally substituted C6-10 aryl, or two of R2a, R2b, R2c, R2d, R, R′, and R″, together with a carbon atom or a nitrogen atom to which they are attached, form a 3- to 6-membered saturated carbocyclic ring or saturated heterocyclic ring, and R3a, R3b, R3c and R5a and R5b, are as defined in the description.
Public/Granted literature
- US20240150370A1 BICYCLIC PYRIDINE DERIVATIVE Public/Granted day:2024-05-09
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