Invention Grant
- Patent Title: Bispecific antibodies for use in the treatment of hematological malignancies
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Application No.: US17277984Application Date: 2019-09-19
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Publication No.: US12077586B2Publication Date: 2024-09-03
- Inventor: Iris De Weerdt , Arnon Philip Kater , Paul Willem Henri Ida Parren , Tanja Denise De Gruijl , Johannes Jelle Van Der Vliet , Roeland Lameris
- Applicant: LAVA THERAPEUTICS N.V.
- Applicant Address: NL Utrecht
- Assignee: LAVA THERAPEUTICS N.V.
- Current Assignee: LAVA THERAPEUTICS N.V.
- Current Assignee Address: NL Utrecht
- Agency: COOLEY LLP
- Priority: NL 21664 2018.09.19
- International Application: PCT/NL2019/050625 2019.09.19
- International Announcement: WO2020/060406A 2020.06.26
- Date entered country: 2021-03-19
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61P35/00 ; A61P35/02

Abstract:
The present invention relates to novel methods for the treatment of hematological malignancies. In particular, the invention relates to the treatment of hematological malignancies using antibodies comprising a first binding moiety that is able to bind human CD1d and a second binding moiety that is able to bind the human Vγ9Vδ2-TCR.
Public/Granted literature
- US20210371525A1 NOVEL BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES Public/Granted day:2021-12-02
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