Invention Grant
- Patent Title: Multispecific antigen-binding molecules for cell targeting and uses thereof
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Application No.: US16993721Application Date: 2020-08-14
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Publication No.: US12077603B2Publication Date: 2024-09-03
- Inventor: Lauric Haber , Jennifer A. Finney , Ryan McKay , Eric Smith , Chia-Yang Lin
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Schwabe, Williamson & Wyatt PC
- Agent Eileen Woo
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K14/725 ; C07K14/74 ; C07K16/46
Abstract:
The present invention provides multispecific antigen-binding molecules that bind both a T-cell antigen (e.g., CD3) and a target antigen (e.g., a tumor associated antigen, a viral or bacterial antigen), and which include a single polypeptide chain that is multivalent (e.g., bivalent) with respect to T-cell antigen binding, and uses thereof.
Public/Granted literature
- US20210047438A1 Multispecific Antigen-Binding Molecules for Cell Targeting and Uses Thereof Public/Granted day:2021-02-18
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