Invention Grant
- Patent Title: Ionizable cationic lipids
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Application No.: US18064565Application Date: 2022-12-12
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Publication No.: US12077725B2Publication Date: 2024-09-03
- Inventor: Daryl C. Drummond , Dmitri B. Kirpotin , Mark E. Hayes
- Applicant: Akagera Medicines, Inc.
- Applicant Address: US MA Boxford
- Assignee: Akagera Medicines, Inc.
- Current Assignee: Akagera Medicines, Inc.
- Current Assignee Address: US MA Boxford
- Agency: Greenberg Traurig, LLP
- Agent David J. Dykeman; Natalie Salem
- Main IPC: C11C3/00
- IPC: C11C3/00 ; C07D317/28 ; C07F9/09
Abstract:
The present disclosure provides compounds useful as ionizable cationic lipids. The ionizable cationic lipids are useful for preparing lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids were engineered with improved stability to oxidative degradation while in storage.
Public/Granted literature
- US20230126953A1 IONIZABLE CATIONIC LIPIDS Public/Granted day:2023-04-27
Information query
