Invention Grant
- Patent Title: Device for dispensing microbubbles for cell sonoporation
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Application No.: US17277351Application Date: 2019-09-18
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Publication No.: US12077744B2Publication Date: 2024-09-03
- Inventor: Anthony Delalande , Matthias Lebertre , Michaël Delalande , Chantal Pichon
- Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , UNIVERSITE D'ORLEANS
- Applicant Address: FR Paris
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS),UNIVERSITE D'ORLEANS
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS),UNIVERSITE D'ORLEANS
- Current Assignee Address: FR Paris; FR Orleans
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Erin M. Dunston
- Priority: FR 58385 2018.09.18
- International Application: PCT/EP2019/075075 2019.09.18
- International Announcement: WO2020/058367A 2020.03.26
- Date entered country: 2021-03-18
- Main IPC: C12M1/42
- IPC: C12M1/42 ; A61B8/00 ; A61M37/00 ; C12M1/36 ; C12N15/87 ; A61B8/08 ; A61B17/22

Abstract:
The invention describes a device (10) for dispensing microbubbles (30) for cell sonoporation, comprising:
a tube configured to receive a vial (20) containing a solution (26) of microbubbles (30),
at least two catheters (11, 12) arranged inside the tube and opening into the vial (20) when the latter is received by the tube,
wherein, when the first catheter (11) is connected to a first air injection source, air can be injected into the vial (20) via the first catheter so as to generate an overpressure therein, the microbubbles (30) contained in the vial (20) entering the second catheter (12) and moving toward its second end (122). The invention also relates to a sonoporation device, a sonoporation process and a computer program product.
a tube configured to receive a vial (20) containing a solution (26) of microbubbles (30),
at least two catheters (11, 12) arranged inside the tube and opening into the vial (20) when the latter is received by the tube,
wherein, when the first catheter (11) is connected to a first air injection source, air can be injected into the vial (20) via the first catheter so as to generate an overpressure therein, the microbubbles (30) contained in the vial (20) entering the second catheter (12) and moving toward its second end (122). The invention also relates to a sonoporation device, a sonoporation process and a computer program product.
Public/Granted literature
- US20220033756A1 DEVICE FOR DISPENSING MICROBEADS FOR CELL SONOPORATION Public/Granted day:2022-02-03
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