Invention Grant
- Patent Title: DNA aptamers and use thereof for the treatment of cancer
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Application No.: US17413550Application Date: 2019-12-16
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Publication No.: US12077760B2Publication Date: 2024-09-03
- Inventor: Gabriel Lopez-Berestein , Paola Amero , Cristian Rodriguez-Aguayo , Rahul Mitra , Anil K. Sood , Vittorio De Franciscis , David Volk , Lokesh Ganesh L. Rao
- Applicant: Board of Regents, The University of Texas System , Consiglio Nazionale delle Ricerche
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System,Consiglio Nazionale delle Ricerche
- Current Assignee: Board of Regents, The University of Texas System,Consiglio Nazionale delle Ricerche
- Current Assignee Address: US TX Austin; IT Rome
- Agency: Parker Highlander PLLC
- International Application: PCT/US2019/066654 2019.12.16
- International Announcement: WO2020/124095A 2020.06.18
- Date entered country: 2021-06-12
- Main IPC: C12N15/115
- IPC: C12N15/115 ; A61K31/337 ; A61K33/243 ; A61P35/00
Abstract:
Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.
Public/Granted literature
- US20220380766A1 DNA APTAMERS AND USE THEREOF FOR THE TREATMENT OF CANCER Public/Granted day:2022-12-01
Information query
IPC分类:
