Invention Grant
- Patent Title: Systems and methods for genetic manipulation of
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Application No.: US17055478Application Date: 2019-05-15
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Publication No.: US12077761B2Publication Date: 2024-09-03
- Inventor: Raphael Valdivia , Per Malkus , Lauren Davey
- Applicant: DUKE UNIVERSITY
- Applicant Address: US NC Durham
- Assignee: DUKE UNIVERSITY
- Current Assignee: DUKE UNIVERSITY
- Current Assignee Address: US NC Durham
- Agency: Quarles & Brady, LLP
- International Application: PCT/US2019/032431 2019.05.15
- International Announcement: WO2019/222359A 2019.11.21
- Date entered country: 2020-11-13
- Main IPC: A61K39/02
- IPC: A61K39/02 ; C12N1/20 ; C12N15/10 ; C12N15/74
Abstract:
The present disclosure provides methods and systems for genetically altering and screening Akkermansia bacteria, including Akkermansia muciniphila. The methods also provide genetically altered bacteria, libraries of genetically altered bacteria and use of such bacteria for treatment of diseases.
Public/Granted literature
- US20210222180A1 SYSTEMS AND METHODS FOR GENETIC MANIPULATION OF AKKERMANSIA SPECIES Public/Granted day:2021-07-22
Information query
