Invention Grant
- Patent Title: Optimized binuclease fusions and methods
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Application No.: US17560522Application Date: 2021-12-23
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Publication No.: US12077790B2Publication Date: 2024-09-03
- Inventor: James Arthur Posada , Sanjay Patel , Weihong Yu , Chris Gabel
- Applicant: Resolve Therapeutics, LLC
- Applicant Address: US FL St. Petersburg
- Assignee: Resolve Therapeutics, LLC
- Current Assignee: Resolve Therapeutics, LLC
- Current Assignee Address: US FL Miami
- Agency: Foley Hoag LLP
- Agent Amy E. Mandragouras; Samantha N. Devenport
- Main IPC: C12N9/22
- IPC: C12N9/22 ; A61K38/00
Abstract:
The invention provides for optimized binuclease fusion proteins with increased pharmacokinetic properties. The optimized binuclease fusion proteins of the invention two or more nuclease domains (e.g., RNase and DNase domain) operably coupled to an Fc domain. The invention also provides methods of treating or preventing a condition associated with an abnormal immune response.
Public/Granted literature
- US20220112474A1 OPTIMIZED BINUCLEASE FUSIONS AND METHODS Public/Granted day:2022-04-14
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