Invention Grant
- Patent Title: PH20 polypeptide variants with a modification at position 309 of the PH20 polypeptide and a method of making thereof
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Application No.: US18339829Application Date: 2023-06-22
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Publication No.: US12077791B2Publication Date: 2024-09-03
- Inventor: Ge Wei , H. Michael Shepard , Qiping Zhao , Robert James Connor
- Applicant: HALOZYME, INC.
- Applicant Address: US CA San Diego
- Assignee: HALOZYME, INC.
- Current Assignee: HALOZYME, INC.
- Current Assignee Address: US CA San Diego
- Agency: Morgan, Lewis & Bockius LLP
- The original application number of the division: US13694731 2012.12.28
- Main IPC: C07K14/00
- IPC: C07K14/00 ; A61K9/00 ; A61K38/00 ; A61K38/16 ; A61K38/28 ; A61K38/43 ; A61K38/47 ; A61K45/06 ; A61K47/10 ; A61P35/00 ; C07K14/47 ; C12N9/26 ; C12Q1/34
Abstract:
Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
Public/Granted literature
- US20240026327A1 PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF Public/Granted day:2024-01-25
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