An information handling system with an antenna cooling system, comprising a processor; a memory; a power management unit (PMU) operatively coupled to the processor; a wireless interface adapter with a radio module within a chassis of the information handling system; and an active antenna system with an antenna mounted at an aperture in a wall of the chassis of the information handling system; a thermally conductive and radio frequency (RF) transparent window formed seamlessly within the aperture in the wall of the chassis of the information handling system and where the thermally conductive and RF transparent window is configured to permit antenna RF transmission while dissipating heat generated by the active antenna system.