An intersection collision avoidance system determines, for an ego vehicle, a direction indicated by its turn signal, its destination setting, or both, generates, where the direction is determined, a possible intended path relative to an intersection using a high-definition (HD) map and the direction, and generates, where the destination setting is determined, a possible intended path for using the HD map and the destination setting. Where the direction and the destination setting are both determined, the direction indicated by the turn signal is compared to the possible intended path generated using the destination setting, and one of the possible intended paths is selected based on the comparison. The system transmits, to a conflict detection module, a set of drive goals for the ego vehicle relative to the intersection that conforms to the intended path. The module can determine a possible collision with another road user using the drive goals.