A display substrate and a display device are provided. The display substrate includes a base substrate and sub-pixels on the base substrate, a sub-pixel includes an organic light emitting element and a pixel circuit, the organic light emitting element includes a first electrode, a light emitting layer and a second electrode which is electrically connected to the pixel circuit. The sub-pixels include first color sub-pixels, second color sub-pixels and third color sub-pixels, current efficiency of a first color sub-pixel is different from that of a second color sub-pixel. The display substrate includes a source-drain metal layer which includes a first power signal line, the display substrate includes a second power signal line and reset power signal lines, the reset power signal lines include a first reset power signal line and a second reset power signal line which are electrically connected to the pixel circuit.