An automatic replacement device of a secondary battery material including reel support parts to support a supply reel; a material support part spaced apart from the reel support part; clamping parts, each including a clamping roller to come into contact with the material when replacing the supply reel, a vacuum suction part to suction the material by vacuum, a clamping frame to rotatably support the clamping roller and the vacuum suction part, and a cutter to cut the material when coming into contact with the material; first drive parts to move the clamping roller toward/away from the material; and second drive parts to move the cutter toward/away from the material, wherein the automatic replacement device cuts the material as the material is suctioned to the vacuum suction part after being adhered to a material wound around a replacement supply reel when the supply reel is replaced.