A voltage-mode transmitter includes a serializer, a pre-driver circuit, a driver circuit, and a resistor calibration circuit. The serializer converts a data into a serial data. The pre-driver circuit drives the serial data. The driver circuit includes a slice, a replica slice, a reference voltage generation circuit, a first operational amplifier, and a second operational amplifier. The reference voltage generation circuit is coupled between a first system voltage and a second system voltage and includes a resistor. The resistor calibration circuit is configured to use a first current source and a reference resistor to generate a reference voltage, the first current source being a current source having been calibrated by a bandgap reference (BGR) circuit; to generate a target voltage by causing a current of a second current source to flow through the resistor; and to adjust the resistor according to the reference voltage and the target voltage.