An anti-electromagnetic interference telescopic boom and a crane. The telescopic boom includes a first anti-interference module, a second anti-interference module and a cable drum; wherein the first anti-interference module, the second anti-interference module and the cable drum are all arranged on a telescopic boom of the crane, the first anti-interference module is connected to a first end of the cable drum, and the second anti-interference module is connected to a second end of the cable drum, the cable drum is configured to transmit a control signal and a power signal for a control system of the telescopic boom, the first anti-interference module is configured to filter and encrypt the control signal and the power signal, and the second anti-interference module is configured to re-filter, decrypt and amplify the control signal and the power signal.