Invention Grant
- Patent Title: Peptide-based compounds for use in the prevention, treatment and/or detection of cancer
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Application No.: US16982095Application Date: 2019-03-18
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Publication No.: US12084511B2Publication Date: 2024-09-10
- Inventor: Edgar Schmitt , Horst Kunz , Natascha Stergiou , Nikola Gaidzik
- Applicant: Universitätsmedizin der Johannes Gutenberg-Universität Mainz
- Applicant Address: DE Mainz
- Assignee: Universitätsmedizin der Johannes Gutenberg-Universität Mainz
- Current Assignee: Universitätsmedizin der Johannes Gutenberg-Universität Mainz
- Current Assignee Address: DE Mainz
- Agency: McHale & Slavin, P.A.
- Priority: EP 163057 2018.03.21
- International Application: PCT/EP2019/056672 2019.03.18
- International Announcement: WO2019/179923A 2019.09.26
- Date entered country: 2020-09-18
- Main IPC: C07K16/30
- IPC: C07K16/30 ; A61P35/00

Abstract:
The present invention relates to a compound comprising a first polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of GFTFSDYW (SEQ ID NO: 1), IRLKSNNYAA (SEQ ID NO: 2) and TFGNSFAY (SEQ ID NO: 3), a second polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of TGAVTTNNY (SEQ ID NO: 4), GTN (SEQ ID NO: 5) and ALWYSNHWV (SEQ ID NO: 6), or a variant of any one of said amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 6 having a different amino acid at one position, wherein said compound or variant is capable of binding to tumour-associated Mucin-1 (TA-MUC1).
Public/Granted literature
- US20210130489A1 Novel peptide-based compounds for use in the prevention, treatment and/or detection of cancer Public/Granted day:2021-05-06
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