Invention Grant
- Patent Title: Optimized CRISPR-Cas nucleases and base editors and methods of use thereof
-
Application No.: US18164910Application Date: 2023-02-06
-
Publication No.: US12084671B2Publication Date: 2024-09-10
- Inventor: Nathaniel Graham
- Applicant: Pairwise Plants Services, Inc.
- Applicant Address: US NC Durham
- Assignee: Pairwise Plants Services, Inc.
- Current Assignee: Pairwise Plants Services, Inc.
- Current Assignee Address: US NC Durham
- Agency: Myers Bigel, P.A.
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N9/22 ; C12N15/113
Abstract:
This invention relates to CRISPR-Cas nucleases codon optimized for expression in plants and nucleic acid constructs encoding base editors comprising a CRISPR-Cas nuclease and a deaminase domain, wherein the nucleic acid constructs are optimized for expression in a plant. The invention further relates to methods of modifying nucleic acids using the nucleic acid constructs.
Public/Granted literature
- US20230183726A1 OPTIMIZED CRISPR-CAS NUCLEASES AND BASE EDITORS AND METHODS OF USE THEREOF Public/Granted day:2023-06-15
Information query
IPC分类:
