A cell potential measurement device has a measuring plane on which a cell suspension is dropped. The cell potential measurement device includes a plurality of working electrodes and a reference electrode. The plurality of working electrodes are two-dimensionally arranged in a working region of the measuring plane. The reference electrode is provided outside the working area of the measuring plane. A contact angle in a hydrophobic region between the working region and the reference electrodes of the measuring plane is larger than a contact angle in the working region.