A method and system for operating an industrial process using an integrated quadratic controller (IQC) is provided for a single input multiple output system (SIMO). A target process value (PV) associated with an output of the industrial process is used to define an optimal output of the industrial process. Manipulated-variables (MVs) associated with a plurality of loads within the industrial process are utilized for controlling a rate of operation associated with the load impacting the PV of the industrial process. Quadratic programming (QP) is defined to optimize proportional action gains for the determined MVs given an update control variable PV. QP gain-modified proportional action are integrated into a control system of the industrial process and a modified control system to update MV output state map defining the multiple output to control respective loads in the industrial control process for achieving the target PV is generated.