A light source driving circuit and a communication device for a display system are provided. The communication device includes a control unit and at least one string light source driving circuit. The control unit includes an output interface for transmitting the control commands or data and a reading back data input interface. Each string light source driving circuit includes a plurality of light source driving circuits. The control unit transmits the control commands or data to the first light source driving circuit of each string light source driving circuit through the output interface. The first driving circuit takes out the commands or data required at the current stage after receiving the control command or data, and then repackages the commands or data of the remaining driving circuits, and transmits the repackaged data packet through the serial output interface and the parallel interfaces or the parallel interfaces.