Invention Grant
- Patent Title: Methods for preparing antibody drug conjugates
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Application No.: US17990988Application Date: 2022-11-21
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Publication No.: US12090211B2Publication Date: 2024-09-17
- Inventor: Thomas Pillow , Peter Dragovich
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Viksnins Harris Padys Malen LLP
- The original application number of the division: US16354905 2019.03.15
- Main IPC: A61K47/68
- IPC: A61K47/68 ; A61K47/65 ; C07K16/22 ; C07K16/28
Abstract:
The subject matter described herein is directed to methods of preparing certain antibody-drug conjugates (ADCs) wherein the antibody is linked to the drug through a linker, wherein the drug contains a heteroaryl group having a secondary nitrogen, and the linker is attached to the drug via the secondary nitrogen. The resulting conjugates are useful in treating various diseases and conditions.
Public/Granted literature
- US20230233700A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES Public/Granted day:2023-07-27
Information query
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