A system and process for receiving email that blocks messages from unwanted automated senders are disclosed. The system is configured to filter automated email from automated senders by way of multiple user-configurable recipient email addresses and corresponding challenge questions to block messages from unwanted automated senders and allow email to be received from wanted automated senders. In this way, the system allows for different recipient addresses to either receive email from automated senders or screen senders with a challenge response, thereby allowing an email user to use the same account to receive both messages from wanted automated senders and messages from human senders. Even if a desired automated sender uses multiple “From” addresses or changes their “From” address unexpectedly, their messages will still be accepted by the system.