The present application relates to a method for managing and controlling a system permission, a data center, a management and control apparatus, and a storage medium. The method for managing and controlling a system permission includes: obtaining personnel change information, wherein the personnel change information includes personal information of a changed person and information about a position change mode of the changed person; obtaining a current permission interface of the changed person based on the personal information; determining, based on the permission interface, whether the changed person has an operation permission for a current object system; if the changed person has the operation permission for the current object system, determining whether the position change mode of the changed person is transfer; sending a notification message if the position change mode of the changed person is the transfer.