Invention Grant
- Patent Title: Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)
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Application No.: US16708232Application Date: 2019-12-09
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Publication No.: US12104207B2Publication Date: 2024-10-01
- Inventor: J. Keith Joung , Shengdar Tsai
- Applicant: The General Hospital Corporation
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: C12Q1/6869
- IPC: C12Q1/6869 ; C12Q1/6855

Abstract:
Unbiased, genomewide and highly sensitive methods for detecting mutations, e.g., off-target mutations, induced by engineered nucleases.
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