Invention Grant
- Patent Title: Assay to detect and quantitate specific antibodies for various redox forms of HMGB1
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Application No.: US17848804Application Date: 2022-06-24
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Publication No.: US12105095B2Publication Date: 2024-10-01
- Inventor: Marie-Lise Gougeon , Nicole Prada , Hela Saidi
- Applicant: INSTITUT PASTEUR
- Applicant Address: FR Paris
- Assignee: INSTITUT PASTEUR
- Current Assignee: INSTITUT PASTEUR
- Current Assignee Address: FR Paris
- Agency: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- Priority: EP 306747 2015.11.03
- The original application number of the division: US15771182
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/68

Abstract:
The quantitation of specific antibodies for at least one redox form of High mobility group box 1 (HMGB1) contained in a biological sample, in particular human serum and/or Cerebrospinal Fluid (CSF) is detailed. An in vitro method for assessing the state of progression of a disease or a disorder in which HMGB1 is involved and an in vitro method for the identification of predisposition, prognostic or diagnostic biomarkers of a disease or a disorder in which
HMGB1 is involved are detailed. A kit to quantitate the specific antibodies for at least one redox form of HMGB1, in particular human HMGB1 is detailed.
HMGB1 is involved are detailed. A kit to quantitate the specific antibodies for at least one redox form of HMGB1, in particular human HMGB1 is detailed.
Public/Granted literature
- US20220317131A1 ASSAY TO DETECT AND QUANTITATE SPECIFIC ANTIBODIES FOR VARIOUS REDOX FORMS OF HMGB1 Public/Granted day:2022-10-06
Information query
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