A multi-stage pressure regulation system, device with enhanced thermal distribution for reducing the pressure of gas passing through a gas sample conditioning system. The device and method allow for automatic and/or manual configuration settings for regulating different types of gas having different profiles while still avoiding dew point dropout thereby ensuring accurate sample analysis at a downstream analyzer. The pressure regulating device includes a housing having a core, a vapor sample input port, a plurality of openings on an upper surface, a plurality of pressure regulating valves configured to reduce the pressure of a vapor sample, an assembly having a base and substantially central stem orthogonal to the base and extending axially therefrom, the stem being disposed within the core, and an adjunct for enhanced distribution of thermal energy from the heating device to the plurality of pressure regulating valves.