A system for optimizing AHB bus data transmission performance includes a master; a decoder connected to the master; a first multiplexer connected to the decoder; and a plurality of slaves connected to the first multiplexer, the decoder, and the master, where the decoder is configured to output a slave selection signal, and determine a slave in transmission communication with the master based on the slave selection signal. The first multiplexer is configured to receive a transmission complete signal output by each slave, and select a transmission complete signal of a corresponding slave based on a first selection signal and output it to the corresponding slave, where the first selection signal is formed by beating the slave selection signal.