A computing system includes one or more processors and a memory. The memory stores instructions that cause the processors to generate a multi-tenant processing environment, and provide, for each of a plurality of tenants, a secure partition to store and isolate data and computational resources of a tenant. The instructions cause the processors to receive, from the tenant, a request to register, with the multi-tenant processing environment, a tenant application to be executed by the secure partition of the tenant. Responsive to the request, the instructions cause the processors to create a partition request message queue, a partition response message queue, and to create, within the secure partition, an application manager. The application manager receives computation parameters from the partition request message queue, passes the computation parameters to the tenant application, receives a computation result from the tenant application, and stores the computation result in the partition response message queue.