A rope-driven soft hand function rehabilitation device includes four finger exoskeleton mechanisms, a thumb exoskeleton mechanism, and a soft rubber glove. An index-finger exoskeleton mechanism includes an index-finger distal phalanx loop, an index-finger middle phalanx loop, and an index-finger proximal phalanx loop which are mutually connected via a hinge structure. The thumb exoskeleton mechanism includes a thumb proximal phalanx loop and a thumb distal phalanx loop which are connected via a hinge structure. The rope is fastened to the hand function rehabilitation device via an aluminum sleeve which prevents the rope from slipping off during finger flexion/extension and abduction/adduction when the fingers are pulled by the rope at the palm and the hand back.