Invention Grant
- Patent Title: S309 chimeric antigen receptors and methods of use
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Application No.: US17551006Application Date: 2021-12-14
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Publication No.: US12109237B2Publication Date: 2024-10-08
- Inventor: Dongfang Liu , Minh Ma , Saiaditya Badeti
- Applicant: Rutgers, The State University of New Jersey
- Applicant Address: US NJ New Brunswick
- Assignee: Rutgers, The State University of New Jersey
- Current Assignee: Rutgers, The State University of New Jersey
- Current Assignee Address: US NJ New Brunswick
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61P31/14 ; C07K14/54 ; C07K14/705 ; C07K14/715 ; C07K14/725 ; C07K16/10 ; A61K38/00 ; A61K39/00
Abstract:
Chimeric antigen receptors (CARs) including an scFv binding to coronavirus spike protein (S309 scFv), nucleic acids encoding the CARs, vectors including nucleic acids encoding the CARs, and cells expressing the CARs are provided. Methods of treating a subject with coronavirus are also provided, including administering to the subject a modified immune cell expressing a disclosed CAR.
Public/Granted literature
- US20220184125A1 S309 CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE Public/Granted day:2022-06-16
Information query
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