Invention Grant
- Patent Title: Use of alveolar or airway organoids for the treatment of lung diseases and disorders
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Application No.: US17074118Application Date: 2020-10-19
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Publication No.: US12109242B2Publication Date: 2024-10-08
- Inventor: Carla F. Kim , Sharon M. Louie , Erhan Ararat , David Raiser
- Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
- Applicant Address: US MA Boston
- Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION
- Current Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION
- Current Assignee Address: US MA Boston
- Agency: NIXON PEABODY LLP
- Agent David S. Resnick; Jeanne N. Jodoin
- Main IPC: C12N5/071
- IPC: C12N5/071 ; A01K67/0271 ; A61K9/00 ; A61K35/42 ; A61K45/06 ; A61K49/00 ; C12N5/00
Abstract:
Various aspects described herein provide methods of generating alveolar or alveolar/airway organoids from a population of lung cells to differentiate into alveolar or alveolar/airway organoids. Also provided herein are methods and compositions for treating lung disease comprising transplantation of the alveolar or alveolar/airway organoids, or a cell isolated therefrom to a subject.
Public/Granted literature
- US20210030811A1 USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEASES AND DISORDERS Public/Granted day:2021-02-04
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