Invention Grant
- Patent Title: Use of IGFBP7 for treating malaria
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Application No.: US17426756Application Date: 2020-01-30
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Publication No.: US12109253B2Publication Date: 2024-10-08
- Inventor: Wenn-Chyau Lee , Laurent Renia
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Troutman Pepper Hamilton Sanders LLP
- Priority: SG 201900872X 2019.01.30
- International Application: PCT/SG2020/050043 2020.01.30
- International Announcement: WO2020/159444A 2020.08.06
- Date entered country: 2021-07-29
- Main IPC: A61K38/36
- IPC: A61K38/36 ; A61K31/137 ; A61K31/155 ; A61K31/357 ; A61K31/366 ; A61K31/4706 ; A61K31/4709 ; A61K31/506 ; A61K31/635 ; A61K31/65 ; A61K38/18 ; A61P33/06

Abstract:
The invention relates to a composition comprising insulin growth factor binding protein 7 (IGFBP7) for treating malaria or reducing the phenomenon of IRB C-endothelial cytoadherence. The composition can further comprise Von Willebrand Factor (VWF) and/or thrombospondin-1 (TSP-1). The composition can also be used as an adjunct therapeutic agent alongside other anti-malarial drugs.
Public/Granted literature
- US20220096604A1 USE OF IGFBP7 FOR TREATING MALARIA Public/Granted day:2022-03-31
Information query
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