Invention Grant
- Patent Title: Modulating gabarap to modulate immunogenic cell death
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Application No.: US17518272Application Date: 2021-11-03
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Publication No.: US12109266B2Publication Date: 2024-10-08
- Inventor: Kenneth C. Anderson , Annamaria Gullà
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee Address: US MA Boston
- Agency: Mueting Raasch Group
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; A61P35/04 ; C07K16/28

Abstract:
The present invention relates, in part, to methods of inducing immunogenic cell death to treat a cancer in a subject comprising administering to the subject a therapeutically effective amount of an agent that increases one or more biomarkers listed in Table 1 in combination with an inducer of immunogenic cell death (ICD).
Public/Granted literature
- US20220211848A1 MODULATING GABARAP TO MODULATE IMMUNOGENIC CELL DEATH Public/Granted day:2022-07-07
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