An example system includes a lead including a first electrode disposed at a first level, a second electrode disposed at a second level, a first group of segmented electrodes disposed at a third level, and a second group of segmented electrodes disposed at a fourth level. The example system also includes a medical device configured to deliver symmetrical electrical stimulation to a patient via the first group of segmented electrodes and the second group of segmented electrodes and sense a response to the stimulation via the first electrode and the second electrode.