An amplifier with stacked transconducting cells in parallel and/or cascade “current mode” combining is disclosed herein. In one or more embodiments, a method for operation of a high-voltage signal amplifier comprises inputting, into each transconducting cell of a plurality of transconducting cells, a direct current (DC) supply current (Idc), an alternating current (AC) radio frequency (RF) input current (IRF_IN), and an RF input signal (RFIN). The method further comprises outputting, by each of the transconducting cells of the plurality of transconducting cells, the DC supply current (Idc) and an AC RF output current (IRF_OUT). In one or more embodiments, the transconducting cells are connected together in cascode for the DC supply current (Idc), are connected together in parallel (or in cascade) for the RF input signal (RFIN), and are connected together in parallel (or in cascade) for the AC RF output currents (IRF_OUT).