Invention Grant
- Patent Title: Portable, low-cost pathogen detection and strain identification platform
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Application No.: US17849250Application Date: 2022-06-24
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Publication No.: US12116623B2Publication Date: 2024-10-15
- Inventor: Alexander Green , Dana Braff , Melissa Takahashi , Keith Pardee , James J. Collins , Guillaume Lambert , Thomas Ferrante
- Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , PRESIDENT AND FELLOWS OF HARVARD COLLEGE , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Applicant Address: US AZ Scottsdale
- Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US AZ Scottsdale; US MA Cambridge; US MA Cambridge
- Agency: Quarles & Brady, LLP
- Main IPC: C12Q1/6827
- IPC: C12Q1/6827 ; C12Q1/6816 ; C12Q1/70
Abstract:
Methods for detecting the presence of a pathogen infection are described. In particular, this document provides a method of detecting target nucleic acids, such as pathogen-specific RNA, in a biological sample obtained from a subject, where the method comprises using one or more toehold switch sensors and an isothermal amplification step to detect the target nucleic acid. Methods specific for detecting and identify the presence of a virus such as Zika virus are also provided.
Public/Granted literature
- US20220411855A1 PORTABLE, LOW-COST PATHOGEN DETECTION AND STRAIN IDENTIFICATION PLATFORM Public/Granted day:2022-12-29
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