An ergonomic chair has a back support member and means for arranging and supporting legs of the user in an asymmetric configuration, with a first leg extending in front of a body of the user and a second leg aligned with or extending behind the body of the user. An angle between the first and second legs in a side view can be at least 30 degrees. The means for arranging and supporting legs can comprise one or more fixed structures that support the first leg in a first orientation, or one or more dynamic structures that can be positioned by the user to support the first leg in a first orientation. In some embodiments, with the legs of the user in the asymmetric configuration, a centerline of the user is offset from a centerline of the back support member with respect to a lateral direction.