A system and method are provided for creating both angiographic images of a subject and dynamic images of the subject from imaging data acquired during an imaging acquisition. The method includes operating an imaging system to perform an imaging acquisition by delivering interspersed doses of high doses of the ionizing radiation and low doses of the ionizing radiation, wherein more low doses of the ionizing radiation are delivered than high doses of ionizing radiation during the imaging acquisition to thereby acquire the imaging data with a high frame rate of low dose data and a low frame rate of high dose data. The method also includes generating at least volumetric angiographic images of the subject and dynamic images of the subject from the imaging data.