Invention Grant
- Patent Title: Oromucosal solutions of zolpidem or pharmaceutically acceptable salts thereof
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Application No.: US17283328Application Date: 2019-10-04
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Publication No.: US12133845B2Publication Date: 2024-11-05
- Inventor: Nisheel K. Patel , Ketan R. Patel , Milan R. Patel , Kush M. Patel , Asheel K. Patel
- Applicant: TROIKAA PHARMACEUTICALS LIMITED
- Applicant Address: IN Ahmedabad
- Assignee: TROIKAA PHARMACEUTICALS LIMITED
- Current Assignee: TROIKAA PHARMACEUTICALS LIMITED
- Current Assignee Address: IN Ahmedabad
- Agency: Baker Hostetler
- Priority: IN201821038060 20181008
- International Application: PCT/IN2019/050734 WO 20191004
- International Announcement: WO2020/075183 WO 20200416
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K9/08 ; A61K47/02 ; A61K47/10 ; A61K47/14 ; A61K47/26 ; A61K47/32 ; A61K47/40
Abstract:
The present invention relates to buccal or sublingual formulations of Zolpidem or pharmaceutically acceptable salt thereof. The formulations minimize the amount of penetration enhancers and yet provide rapid transmucosal penetration of the drug. These formulations not only provide desired a concentration (0.5% to 10% w/v) of the drug in the form of clear solution, but also achieve stable formulations throughout the shelf-life of at least about 2 years. The pH of the stable non-aqueous solutions of the present invention is in the range of range of 5 to 9, preferably 6 to 9 more preferably 7 to 9.
Public/Granted literature
- US20220000845A1 OROMUCOSAL SOLUTIONS OF ZOLPIDEM OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Public/Granted day:2022-01-06
Information query
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